Mother's Antibody Cause Autism

Based on research conducted by the John Hopkins Children's Investigators found that mothers of children suffering from autism have antibodies that can cause interference with the fetus while in the womb. These antibodies can cross the placenta and cause changes that lead to autism. Another study in Sacramento, California by Davis MIND Institute and Center for Children's Environmental Health also found that antibodies in pregnant mother's body bind to fetal brain cells, which likely interfere with brain development that could affect the autism.

Autism itself is a disorder with a major problem in the brain and disorders characterized by social interaction, communication and behavior disorders over, and 90% of those with no known cause. Genetic, metabolic, and environmental factors associated with the estimated cause autism. This research started from the acquisition of an antibody levels are not unusual in children suffering from autism and from postmortem brain tissue (already dead), which provides an immunity disorders (immune system) in the area of the brain. Antibodies are proteins in the body respond to viruses and bacteria or sometimes in a few cases of autoimmune disorders, antibodies may attack the body's own cells.

The majority of children with autism do not have an autoimmune disease that question to be answered is whether the antibodies found in here are an antibody provided by the mother while in the womb that can interfere with fetal brain directly.

To try out their hypotheses (John Hopkins), the research team used a technique called imunoblotting (Western blot technology) where the antibody is derived from blood samples of brain tissue exposed to adult and fetus to confirm whether these antibodies recognize and react with specific brain proteins.

Comparing antibody and brain interactions in a sample of 100 mothers with autistic children and 100 mothers with children without autism. Researchers found a greater reactivity of approximately 40% of mothers with children with autism. Furthermore, the presence of maternal antibodies associated with a reduction in the development of the child who is one of the signs of autism.

Although the study found a link between autism and the fetal brain antibodies, but further research is still needed to confirm whether these antibodies can cross the placenta and cause fetal brain damage.

Facts which pregnant women with antibodies can cause fetal brain damage, does not mean that she will always have a child with autism disorders. Autism itself is a complex condition caused by interaction between genetic factors, immunity, and environmental factors.