Physical activity of sports, daily activities and even danced a useful routine to prevent atherosclerosis (fatty deposits in artery walls). This was proven by autopsy Boston marathon champion seven times, Clarence deMar, which indicates the size of coronary arteries from two to three times its normal size and did not find any stenosis (narrowing of blood vessels) is significant even died at the age of 69 years.
Relation of physical activity to the prevention of coronary heart disease due to atherosclerosis is discussed Dr. Dede Kusmana SpJP dr (K) (60), in a speech at the inauguration ceremony as Professor of Cardiology Stay in the Science Faculty of Medicine at the University of Indonesia, Wednesday (18 / 6).
According to Dede who is also Chairman of the Section of Cardiology FKUI, especially aerobic physical activity increases blood flow which is a wave that encourage increased production of nitric oxide (NO) and stimulate the formation and derive the release of endothelial relaxing factor (EDRF), which relax and dilate blood vessels.
Coronary blood flow during rest, about 200 ml per minute (four per cent of the total cardiac output). Research in the laboratory showed that increased blood flow 4 ml per minute was able to produce NO to stimulate endothelial function improvement (lining) of blood vessels.
"Therefore, physical activity is a gym or walking are increased blood flow to 350 ml per minute (up 150 ml per minute) was more than enough to prevent blood vessels from endothelial atherosclerosis process," said Dede.
However, the benefits could be obtained only if the increased blood flow through the physical activity took place regularly in a long time (20 minutes to an hour) and regular life.
Mechanism of atherosclerosisDede explains, atherosclerosis begins with mainly cholesterol ester accumulation, LDL cholesterol (low density lipoproteins) in the artery wall. LDL normally get in and out of the artery through the endothelial wall. The entry of lipoproteins into the inner lining of blood vessel walls to rise as the high number of plasma lipoproteins (hyperlipidemia), the size of lipoprotein and blood pressure (hypertension). Increasing it will increase the permeability of the blood vessel walls, so that lipoproteins and cholesterol esters in the arterial wall settles.
Malfunctioning of the blood vessel lining became the beginning of the process of atherosclerosis and promote the mechanism of inflammation and infection.
Inflammation or inflammation of the body's basic response to injury (wound). Injuries are usually caused by infection, but can also as allergic or immunological reactions. Clinical manifestations of the complex process of atherosclerosis is coronary heart disease, stroke and even death.
According to the Framingham study, so Dede, C-reactive protein (CRP) is a sign (marker) inflammation associated with cardiovascular events or stroke. Efforts to suppress inflammatory factors may prevent the process of atherosclerosis. Regular physical activity proved to suppress the CRP, is also suppress inflammatory factors.
Therefore, moving or doing regular physical activity is an early concept of cardiovascular disease prevention and rational efforts for patients with cardiovascular disorders in cardiac rehabilitation.
Endurance exercise combined with weight training for four months proved to reduce levels of TNF alpha (a type of inflammatory cytokine) significantly in patients with heart failure and coronary heart disease.
Type of activityIn healthy people, the prevalence of hypertension, hyperlipidemia, and ischemia (blood deficiency conditions in the network) is lower in people with more severe physical activity and regular than the irregular or no exercise.
May be concluded, regular physical activity has a power protection against cardiovascular death and other diseases due to lifestyle (non-communicable disease).
No need to exercise a difficult and expensive. Walk six miles per hour, the burden is aerobics, dancing was sufficient to maintain cardiovascular health. Similarly, activities such as climbing stairs equivalent two-level, carrying 10 kilograms, hoe, or gardening.
"Anything activity can increase heart rate between 110-130 beats per minute, accompanied by sweating and increased respiratory rate but not until the panting good enough to prevent heart disease and stroke," explained Dede. (ATK)